Standard Curve (Sample)
C1 Inhibitor Total Antigen ELISA Kit | HC1INHKT-TOT elisa kit
Human C1 Inhibitor Total Antigen ELISA Kit
Gene Names
SERPING1; C1IN; C1NH; HAE1; HAE2; C1INH
Synonyms
C1 Inhibitor Total Antigen; N/A; Human C1 Inhibitor Total Antigen ELISA Kit; Plasma Protein ELISA Kits, Human Kits; HC1INHKT-TOT elisa kit
Specificity
These studies are currently in progress. Please contact us for more information.
Sequence Length
500
Sensitivity
0.9 ng/ml
Intra-assay Precision
These studies are currently in progress. Please contact us for more information.
Inter-assay Precision
These studies are currently in progress. Please contact us for more information.
Standard Curve (Sample)
Standard Curve (Sample)
Related Product Information for HC1INHKT-TOT elisa kit
Background: Plasma protease C1 inhibitor (aka C1 esterase inhibitor or SerpinG1) is a single-chain, 478 amino acid glycoprotein that regulates classical complement activation and the contact activation or intrinsic coagulation pathway [1]. This 105 kDa serine protease inhibitor has a C-terminal serpin domain with unique stabilizing disulfide bonds and highly glycosylated N-terminal domain [2]. C1 inhibitor irreversibly inactivates C1r, C1s, MASP1, MASP2, plasma kallikrein, thrombin, plasmin, tPA, and Factors XIa and XIIa [3]. Genetic deficiency in plasma C1 inhibitor results in Type I hereditary angioedema [4].
Principle of the Assay: Human C1 inhibitor will bind to the affinity purified capture antibody coated on the microtiter plate. Free and complexed C1 inhibitor will react with the antibody on the plate. After appropriate washing steps, horseradish peroxidase labeled polyclonal anti-human C1 inhibitor antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human C1 inhibitor. Color development is directly proportional to the concentration of total C1 inhibitor in the samples.
Intended Uses: This human complement 1 (C1) inhibitor antigen assay is intended for the quantitative determination of total C1 inhibitor antigen in human plasma and serum.
Principle of the Assay: Human C1 inhibitor will bind to the affinity purified capture antibody coated on the microtiter plate. Free and complexed C1 inhibitor will react with the antibody on the plate. After appropriate washing steps, horseradish peroxidase labeled polyclonal anti-human C1 inhibitor antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human C1 inhibitor. Color development is directly proportional to the concentration of total C1 inhibitor in the samples.
Intended Uses: This human complement 1 (C1) inhibitor antigen assay is intended for the quantitative determination of total C1 inhibitor antigen in human plasma and serum.
Product Categories/Family for HC1INHKT-TOT elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
55,769 Da
NCBI Official Full Name
Plasma protease C1 inhibitor
NCBI Official Synonym Full Names
serpin family G member 1
NCBI Official Symbol
SERPING1
NCBI Official Synonym Symbols
C1IN; C1NH; HAE1; HAE2; C1INH
NCBI Protein Information
plasma protease C1 inhibitor
UniProt Protein Name
Plasma protease C1 inhibitor
UniProt Gene Name
SERPING1
UniProt Synonym Gene Names
C1IN; C1NH; C1 Inh; C1Inh
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Product Notes
The HC1INHKT-TOT serping1 (Catalog #AAA37861) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "C1 Inhibitor Total Antigen, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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