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product-image-AAA113279_SDS_PAGE15.jpg SDS-PAGE

Collagen alpha-1(XII) chain Recombinant Protein | COL12A1 recombinant protein

Recombinant Gallus gallus Collagen alpha-1(XII) chain

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Collagen alpha-1(XII) chain; N/A; Recombinant Gallus gallus Collagen alpha-1(XII) chain; Fibrochimerin; COL12A1 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
139-311aa; Partial
Sequence
DLVFLVDGSWSVGRNNFRYILDFMVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYFRRSDLLDAIKRIPYKGGNTMTGEAIDYLVKNTFTESAGARKGFPKVAIVITDGKAQDEVEIPARELRNIGVEVFSLGIKAADAKELKLIASQPSLKHVFNVANFDGIVDIQNEI
Sequence Length
1,960
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

product-image-AAA113279_SDS_PAGE15.jpg SDS-PAGE
Related Product Information for COL12A1 recombinant protein
Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.
References
The complete primary structure of type XII collagen shows a chimeric molecule with reiterated fibronectin type III motifs, von Willebrand factor A motifs, a domain homologous to a noncollagenous region of type IX collagen, and short collagenous domains with an Arg-Gly-Asp site.Yamagata M., Yamada K.M., Yamada S.S., Shinomura T., Tanaka H., Nishida Y., Obara M., Kimata K.J. Cell Biol. 115:209-221(1991) Type XII collagen. A large multidomain molecule with partial homology to type IX collagen.Gordon M.K., Gerecke D.R., Dublet B., van der Rest M., Olsen B.R.J. Biol. Chem. 264:19772-19778(1989) Type XII collagen distinct extracellular matrix component discovered by cDNA cloning.Gordon M.K., Gerecke D.R., Olsen B.R.Proc. Natl. Acad. Sci. U.S.A. 84:6040-6044(1987) The two splice variants of collagen XII share a common 5' end.Trueb J., Trueb B.Biochim. Biophys. Acta 1171:97-98(1992) Large and small splice variants of collagen XII differential expression and ligand binding.Koch M., Bohrmann B., Matthison M., Hagios C., Trueb B., Chiquet M.J. Cell Biol. 130:1005-1014(1995)

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
21.3 kDa
NCBI Official Full Name
Collagen alpha-1(XII) chain
UniProt Protein Name
Collagen alpha-1(XII) chain
UniProt Gene Name
COL12A1
UniProt Entry Name
COCA1_CHICK

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Product Notes

The COL12A1 col12a1 (Catalog #AAA113279) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 139-311aa; Partial. The amino acid sequence is listed below: DLVFLVDGSW SVGRNNFRYI LDFMVALVSA FDIGEEKTRV GVVQYSSDTR TEFNLNQYFR RSDLLDAIKR IPYKGGNTMT GEAIDYLVKN TFTESAGARK GFPKVAIVIT DGKAQDEVEI PARELRNIGV EVFSLGIKAA DAKELKLIAS QPSLKHVFNV ANFDGIVDIQ NEI. It is sometimes possible for the material contained within the vial of "Collagen alpha-1(XII) chain, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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