Bioactivity
(Human RAET1L/ULBP6 is coated at 10 ug/ml (100 ul/well) can bind Human NKG2D (CAT# ATGP3662) in a Functional ELISA assay.)
ULBP-6/RAET1L active protein
Recombinant human ULBP-6/RAET1L Protein
Applications
SDS-Page
Purity
>95% by SDS-PAGE
Synonyms
ULBP-6/RAET1L; N/A; Recombinant human ULBP-6/RAET1L Protein; early transcript 1L; ULBP6; UL16-binding protein 6;RAET1L; retinoic acid early transcript 1L protein; retinoic acid early transcript 1L; ULBP-6/RAET1L active protein
Host
Baculovirus
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid. In Phosphate-Buffered Saline (pH7.4) containing 10% glycerol
Concentration
1mg/ml (determined by Absorbance at 280nm) (varies by lot)
Sequence Positions
26-218aa
Sequence
Applicable Applications for ULBP-6/RAET1L active protein
Bioactivity, SDS-PAGE
Endotoxin
<1 EU per 1ug of protein (determined by LAL method)
Species
Human
Tag
His-Tag
Predicted N-term
Ala
Bioactivity
Measured by its binding ability in a functional ELISA with Human NKG2D.
Preparation and Storage
Can be stored at +2C to +8 degree C for 1 week. For long term storage, aliquot and store at -20C to -80 degree C. Avoid repeated freezing and thawing cycles.
Bioactivity
(Human RAET1L/ULBP6 is coated at 10 ug/ml (100 ul/well) can bind Human NKG2D (CAT# ATGP3662) in a Functional ELISA assay.)
Bioactivity
(Human RAET1L/ULBP6 is coated at 10 ug/ml (100 ul/well) can bind Human NKG2D (CAT# ATGP3662) in a Functional ELISA assay.)
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stainLane 1 : reducing conditionLane 2 : non-reducing condition)
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stainLane 1 : reducing conditionLane 2 : non-reducing condition)
Related Product Information for ULBP-6/RAET1L active protein
RAET1L, also known as retinoic acid early transcript 1L, linked to the cell membrane by the GPI anchor. This protein functions as a stress-induced ligand for NKG2D receptor. Its expression is, for example, triggered in course of HCMV infection, but HCMV alters its function. HCMV-encoded UL16 glycoprotein retains RAET1L/ULBP6 inside the cells, preventing it from reaching the cell surface and being exposed to cells of the immune system. It had a more restricted expression pro?le in cell lines and primary human tissues than other NKG2D ligands. RAET1L mRNA shows restricted expression in the trachea and some HPV positive cervical carcinoma and colorectal carcinoma cell lines. Recombinant human RAET1L, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Categories/Family for ULBP-6/RAET1L active protein
References
Eagle R.A., et al. (2009) Eur. J. Immunol. 39:3207. Kondo M., et al. (2010) Immunogenetics 62:441.
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
22.9kDa (202aa)
UniProt Protein Name
Retinoic acid early transcript 1L protein
UniProt Gene Name
RAET1L
UniProt Entry Name
RET1L_HUMAN
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Product Notes
The ULBP-6/RAET1L raet1l (Catalog #AAA48398) is an Active Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 26-218aa. AAA Biotech's ULBP-6/RAET1L can be used in a range of immunoassay formats including, but not limited to, Bioactivity, SDS-PAGE. Researchers should empirically determine the suitability of the ULBP-6/RAET1L raet1l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below:Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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