Rabbit TWEAK Polyclonal Antibody | anti-TNFSF12 antibody

TWEAK Antibody

Cat. Num. AAA39826

• Gene Names: TNFSF12; APO3L; DR3LG; TWEAK
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: TWEAK Antibody is Protein A-purified.
• Synonyms: TWEAK, Antibody; TWEAK Antibody; TWEAK; APO3L; DR3LG; UNQ181/PRO207; Tumor necrosis factor ligand superfamily member 12; APO3 ligand; tumor necrosis factor (ligand) superfamily, member 12; anti-TNFSF12 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: TWEAK Antibody is Protein A-purified.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 249

• Applicable Applications for anti-TNFSF12 antibody: IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: TWEAK antibody was raised against recombinant human TWEAK protein.
• Buffer: TWEAK Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: TWEAK antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of TWEAK in mouse brain tissue with TWEAK antibody at 20 μg/mL.Red: TWEAK Antibody (3791)Blue: DAPI staining)

IHC (Immunohistochemisry)

(Immunohistochemistry of TWEAK in mouse brain tissue with TWEAK antibody at 5 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of TWEAK in human brain tissue with TWEAK antibody at 10 μg/mL.)

WB (Western Blot)

(Western blot analysis of TWEAK in HeLa cell lysate with TWEAK antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-TNFSF12 antibody

TWEAK Antibody: TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.

NCBI and Uniprot Product Information

• NCBI GI #: 4507597
• NCBI GeneID: 8742
• NCBI Accession #: NP_003800
• NCBI GenBank Nucleotide #: NM_003809.2
• UniProt Accession #: O43508; Q8IZK7; Q8WUZ7
• Molecular Weight: Predicted: 27 kDa
• NCBI Official Full Name: tumor necrosis factor ligand superfamily member 12 proprotein
• NCBI Official Synonym Full Names: tumor necrosis factor (ligand) superfamily, member 12
• NCBI Official Symbol: TNFSF12
• NCBI Official Synonym Symbols: APO3L; DR3LG; TWEAK
• NCBI Protein Information: tumor necrosis factor ligand superfamily member 12; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis
• UniProt Protein Name: Tumor necrosis factor ligand superfamily member 12
• UniProt Gene Name: TNFSF12
• UniProt Synonym Gene Names: APO3L; DR3LG; TWEAK
• UniProt Entry Name: TNF12_HUMAN