IHC (Immunohiostchemistry)
(Anti-NMDAR1 antibody, AAA44973, IHC(P)IHC(P): Rat Brain Tissue)
Rabbit NMDAR1 Polyclonal Antibody | anti-GRIN1 antibody
Anti-NMDAR1 antibody
Gene Names
GRIN1; NR1; MRD8; GluN1; NMDA1; NMDAR1
Reactivity
Reacts with: Human, ratPredicted to work with: Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
NMDAR1, Antibody; Anti-NMDAR1 antibody; Glutamate[NMDA] receptor subunit zeta-1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; GluN1 antibody; Glutamate[NMDA] receptor subunit zeta 1 antibody; Glutamate[NMDA] receptor subunit zeta-1 antibody; Glutamate receptor ionotropic N methyl D aspartate 1 antibody; Grin 1 antibody; Grin1 antibody; MRD8 antibody; N methyl D aspartate receptor antibody; N methyl D aspartate receptor channel antibody; N methyl D aspartate receptor channel subunit zeta 1 antibody; N methyl D aspartate receptor subunit NR1 antibody; N-methyl-D-aspartate receptor antibody; N-methyl-D-aspartate receptor subunit NR1 antibody; NMD-R1 antibody; NMDA 1 antibody; NMDA NR1 antibody; NMDA R1 antibody; NMDA receptor 1 antibody; NMDA1 antibody; NMDAR 1 antibody; NMDAR antibody; Nmdar1 antibody; NMDZ1_HUMAN antibody; NR 1 antibody; NR1 antibody; anti-GRIN1 antibody
Host
Rabbit
Reactivity
Reacts with: Human, rat
Predicted to work with: Mouse
Predicted to work with: Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
938
Applicable Applications for anti-GRIN1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human GRIN1 (36-53aa RKHEQMFREAVNQANKRH), identical to the related rat and mouse sequences.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-NMDAR1 antibody, AAA44973, IHC(P)IHC(P): Rat Brain Tissue)
IHC (Immunohiostchemistry)
(Anti-NMDAR1 antibody, AAA44973, IHC(P)IHC(P): Rat Brain Tissue)
WB (Western Blot)
(Anti-NMDAR1 antibody, AAA44973, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Brain Tissue LysateLane 3: Rat Liver Tissue LysateLane 4: Rat Heart Tissue LysateLane 5: MM453 Cell LysateLane 6: MM231 Cell LysateLane 7: HELA Cell Lysate)
WB (Western Blot)
(Anti-NMDAR1 antibody, AAA44973, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Brain Tissue LysateLane 3: Rat Liver Tissue LysateLane 4: Rat Heart Tissue LysateLane 5: MM453 Cell LysateLane 6: MM231 Cell LysateLane 7: HELA Cell Lysate)
Related Product Information for anti-GRIN1 antibody
Description: Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, NMDA 1(GRIN1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: The NMDA receptor(NMDAR) is a specific type of ionotropic glutamate receptor. NMDA(N-methyl D-aspartate) is the name of a selective agonist that binds to NMDA receptors but not to other glutamate receptors. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. NMDAR1 gene is mapped to 9q34.3 and encodes a 938-amino acid protein which showed high evolutionary conservation in structure and physiologic properties. It consists of 21 exons distributed over about 31 kb. Three of the exons that are alternatively spliced in the rat and which produce 8 isoforms in that species were also present in the human sequence. The promoter region contained 2 DNA binding sites for the homeobox proteins 'even-skipped'. The gene is a candidate for the site of the mutation in torsion dystonia.The NMDA receptor is a non-specific cation channel and thus directly contributes to excitatory synaptic transmission by depolarizing the postsynaptic cell. NMDA receptors are modulated by a number of endogenous and exogenous compounds and play a key role in a wide range of physiologic and pathologic processes, such as excitotoxicity.
Background: The NMDA receptor(NMDAR) is a specific type of ionotropic glutamate receptor. NMDA(N-methyl D-aspartate) is the name of a selective agonist that binds to NMDA receptors but not to other glutamate receptors. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. NMDAR1 gene is mapped to 9q34.3 and encodes a 938-amino acid protein which showed high evolutionary conservation in structure and physiologic properties. It consists of 21 exons distributed over about 31 kb. Three of the exons that are alternatively spliced in the rat and which produce 8 isoforms in that species were also present in the human sequence. The promoter region contained 2 DNA binding sites for the homeobox proteins 'even-skipped'. The gene is a candidate for the site of the mutation in torsion dystonia.The NMDA receptor is a non-specific cation channel and thus directly contributes to excitatory synaptic transmission by depolarizing the postsynaptic cell. NMDA receptors are modulated by a number of endogenous and exogenous compounds and play a key role in a wide range of physiologic and pathologic processes, such as excitotoxicity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
101,851 Da
NCBI Official Full Name
Glutamate receptor ionotropic, NMDA 1
NCBI Official Synonym Full Names
glutamate receptor, ionotropic, N-methyl D-aspartate 1
NCBI Official Symbol
GRIN1
NCBI Official Synonym Symbols
NR1; MRD8; GluN1; NMDA1; NMDAR1
NCBI Protein Information
glutamate receptor ionotropic, NMDA 1; NMD-R1; glutamate [NMDA] receptor subunit zeta 1; glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; N-methyl-D-aspartate receptor channel, subunit zeta-1
UniProt Protein Name
Glutamate receptor ionotropic, NMDA 1
UniProt Gene Name
GRIN1
UniProt Synonym Gene Names
NMDAR1; GluN1; NMD-R1
UniProt Entry Name
NMDZ1_HUMAN
Similar Products
Product Notes
The GRIN1 grin1 (Catalog #AAA44973) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NMDAR1 antibody reacts with Reacts with: Human, rat Predicted to work with: Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NMDAR1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GRIN1 grin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NMDAR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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