Rabbit IKK gamma Polyclonal Antibody | anti-IKBKG antibody

IKK gamma Antibody

Cat. Num. AAA39228

• Gene Names: IKBKG; IP; IP1; IP2; FIP3; IPD2; NEMO; FIP-3; Fip3p; IMD33; AMCBX1; ZC2HC9; IKK-gamma
• Reactivity: Human, Mouse, Rat
• Applications: Immunocytochemistry, Western Blot, ELISA
• Purity: IKK gamma Antibody is DEAE purified.
• Synonyms: IKK gamma, Antibody; IKK gamma Antibody; IKK gamma; IP; IP1; IP2; FIP3; IPD2; NEMO; FIP-3; Fip3p; AMCBX1; ZC2HC9; IKK-gamma; NF-kappa-B essential modulator; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; anti-IKBKG antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: IKK gamma has no cross response to IKK alpha or IKK beta.
• Purity/Purification: IKK gamma Antibody is DEAE purified.
• Form/Format: Liquid
• Sequence Length: 1994

• Applicable Applications for anti-IKBKG antibody: ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: IKK gamma antibody was raised against a 17 amino acid peptide near the carboxy terminus of human IKK gamma.
• Buffer: IKK gamma Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: IKK gamma antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of IKK gamma in Hela cells with IKK gamma antibody at 20 μg/mL.Red: IKK gamma Antibody (2335)Blue: DAPI staining)

ICC (Immunocytochemistry)

(Immunocytochemistry of IKK gamma in HeLa cells with IKK gamma antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of IKK gamma in HeLa whole cell lysate with IKK gamma antibody at 1 μg/mL.)

Related Product Information for anti-IKBKG antibody

IKK gamma Antibody: Nuclear factor kappa B (NF-κB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-κB is associated with IκB proteins in the cell cytoplasm, which inhibit NF-κB activity. The IκB kinase (IKKα and IKKβ) phosphorylates IkB and mediates NF-κB activation. A novel molecule in the IKK complex was recently identified and termed IKKγ/NEMO/FIP3/IKKAP1. IKKγ interacts with IKKβ and is required for the activation of IKK complex and NF-κB by LPS, PMA, TNF, and IL-1 stimulation. FIP3 was also shown to bind to RIP and NIK and to mediate TNF-induced NF-κB activation.

NCBI and Uniprot Product Information

• NCBI GI #: 3641279
• NCBI GeneID: 8517
• UniProt Accession #: Q9Y6K9; Q7LBY6; Q7Z7F1
• Molecular Weight: 52 kDa
• NCBI Official Full Name: Homo sapiens IkB kinase gamma subunit (IKK-gamma) mRNA, complete cds
• NCBI Official Synonym Full Names: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
• NCBI Official Symbol: IKBKG
• NCBI Official Synonym Symbols: IP; IP1; IP2; FIP3; IPD2; NEMO; FIP-3; Fip3p; IMD33; AMCBX1; ZC2HC9; IKK-gamma
• NCBI Protein Information: NF-kappa-B essential modulator; IKKG; IKKAP1; incontinentia pigmenti; IkB kinase gamma subunit; ikB kinase subunit gamma; NFkappaB essential modulator; NF-kappa-B essential modifier; I-kappa-B kinase subunit gamma; ikB kinase-associated protein 1; inhibitor of nuclear factor kappa-B kinase subunit gamma
• UniProt Protein Name: NF-kappa-B essential modulator
• UniProt Gene Name: IKBKG
• UniProt Synonym Gene Names: FIP3; NEMO; NEMO; IKKAP1; I-kappa-B kinase subunit gamma; IKK-gamma; IKKG; IkB kinase subunit gamma
• UniProt Entry Name: NEMO_HUMAN