IHC (Immunohistochemisry)
(Anti- CD62P antibody, AAA44923, IHC(P)IHC(P): Human Mammary Cancer Tissue)
Rabbit anti-Human CD62P Polyclonal Antibody | anti-SELP antibody
Anti-CD62P antibody
Gene Names
SELP; CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
CD62P, Antibody; Anti-CD62P antibody; P-selectin; selectin P(granule membrane protein 140kDa, antigen CD62); Antigen CD62 antibody; CD62 antibody; CD62 antigen-like family member P antibody; CD62P antibody; CD62P antigen antibody; FLJ45155 antibody; GMP 140 antibody; GMP-140 antibody; GMP140 antibody; GMRP antibody; Granule membrane protein 140 antibody; Granule membrane protein 140kDa antibody; Granulocyte membrane protein antibody; GRMP antibody; LECAM 3 antibody; LECAM3 antibody; Leukocyte endothelial cell adhesion molecule 3 antibody; Leukocyte-endothelial cell adhesion molecule 3 antibody; LYAM3_HUMAN antibody; P Selectin antibody; P-selectin antibody; PADGEM antibody; Platelet activation dependent granule external membrane protein antibody; Platelet activation dependent granule-external membrane protein antibody; Platelet alpha granule membrane protein antibody; PSEL antibody; Selectin P(granule membrane protein 140kDa antigen CD62) antibody; Selectin P(granule membrane protein 140kDa, antigen CD62) antibody; SELP antibody; anti-SELP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
830
Applicable Applications for anti-SELP antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human CD62P (49-66aa KAYSWNISRKYCQNRYTD).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Relevant Detection Systems
The lab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG ( ) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit ( ) for IHC(P).
Preparation and Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemisry)
(Anti- CD62P antibody, AAA44923, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohistochemisry)
(Anti- CD62P antibody, AAA44923, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti- CD62P antibody, AAA44923, IHC(P)IHC(P): Human Placenta Tissue)
IHC (Immunohiostchemistry)
(Anti- CD62P antibody, AAA44923, IHC(P)IHC(P): Human Placenta Tissue)
WB (Western Blot)
(Anti- CD62P antibody, AAA44923, Western blottingAll lanes: Anti CD62P (AAA44923) at 0.5ug/mlWB: PANC Whole Cell Lysate at 40ugPredicted bind size: 91KDObserved bind size: 140KD)
WB (Western Blot)
(Anti- CD62P antibody, AAA44923, Western blottingAll lanes: Anti CD62P (AAA44923) at 0.5ug/mlWB: PANC Whole Cell Lysate at 40ugPredicted bind size: 91KDObserved bind size: 140KD)
Related Product Information for anti-SELP antibody
Background: P-Selectin, also called CD62, GRMP, GMP140 is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. The P-Selectin gene is mapped on 1q24.2. P-selectin plays an essential role in the initial recruitment of leukocytes(white blood cells) to the site of injury during inflammation. P-selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury. In quiescent platelet, P-selectin is located on the inner wall of alpha-granules. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and suggested that SNX17 may function in the intracellular trafficking of P-selectin. P-selectin expression was found to be significantly and positively correlated with carotid artery stiffness and wall thickness, and the percentage of P-selectin-positive platelets was significantly higher in patients with carotid plaque.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
P-selectin
NCBI Official Synonym Full Names
selectin P (granule membrane protein 140kDa, antigen CD62)
NCBI Official Symbol
SELP
NCBI Official Synonym Symbols
CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM
NCBI Protein Information
P-selectin; GMP-140; granule membrane protein 140; granulocyte membrane protein; CD62 antigen-like family member P; platelet alpha-granule membrane protein; leukocyte-endothelial cell adhesion molecule 3; platelet activation dependent granule-external membrane protein
UniProt Protein Name
P-selectin
UniProt Gene Name
SELP
UniProt Synonym Gene Names
GMRP; GRMP; GMP-140; LECAM3; PADGEM
UniProt Entry Name
LYAM3_HUMAN
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Product Notes
The SELP selp (Catalog #AAA44923) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD62P antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD62P can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the SELP selp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD62P, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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