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product-image-AAA124379_SC15.jpg Standard Curve (Sample) (Typical Testing Data/Standard Curve (for reference only))

Mouse Tumor Necrosis Factor Receptor Superfamily Member 1B, Tnfrsf1b ELISA Kit | Tnfrsf1b elisa kit

Mouse Tumor Necrosis Factor Receptor Superfamily Member 1B, Tnfrsf1b Primacu ELISA Kit

Gene Names
Tnfrsf1b; p75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2
Reactivity
Mouse
Synonyms
Tumor Necrosis Factor Receptor Superfamily Member 1B, Tnfrsf1b; N/A; Mouse Tumor Necrosis Factor Receptor Superfamily Member 1B, Tnfrsf1b Primacu ELISA Kit; Tumor necrosis factor receptor superfamily member 1B; TNFR-2 ; Tnfr-2; Tnfr2; Tnfrsf1b elisa kit
Ordering
Reactivity
Mouse
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
9.38-600pg/mL
Sensitivity
2.1pg/mL
Standard Solution
6ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C

Standard Curve (Sample)

(Typical Testing Data/Standard Curve (for reference only))

product-image-AAA124379_SC15.jpg Standard Curve (Sample) (Typical Testing Data/Standard Curve (for reference only))
Related Product Information for Tnfrsf1b elisa kit
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFRSF1B is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. TNFR2/CD120b/TNFRSF1B is not a major contributing factor to the genetic risk of type 2 diabetes, its associated peripheral neuropathy and hypertension and related metabolic traits in North Indians. Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B) has been reported to be associated with SLE risk in Japanese populations. TNFR2/CD120b/TNFRSF1B serves as a receptor with high affinity for TNFSF2 and approximately 5-fold lower affinity for homotrimeric TNFSF1. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
Product Categories/Family for Tnfrsf1b elisa kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,320 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 1B
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 1b
NCBI Official Symbol
Tnfrsf1b
NCBI Official Synonym Symbols
p75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2
NCBI Protein Information
tumor necrosis factor receptor superfamily member 1B; TNF receptor beta chain; TNF-RII; TNFR-II; p75 TNFR; p80 TNF-alpha receptor; tumor necrosis factor receptor 2; tumor necrosis factor receptor type II
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 1B
UniProt Gene Name
Tnfrsf1b
UniProt Synonym Gene Names
Tnfr-2; Tnfr2; TNF-R2; TNF-RII; TNFR-II
UniProt Entry Name
TNR1B_MOUSE

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Product Notes

The Mouse Tnfrsf1b tnfrsf1b (Catalog #AAA124379) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124379 ELISA Kit recognizes Mouse Tnfrsf1b. It is sometimes possible for the material contained within the vial of "Tumor Necrosis Factor Receptor Superfamily Member 1B, Tnfrsf1b, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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