Application Data
(Immobilized human CD79b His at16 ug/mL can bind Anti-CD79b Reference Antibody (polatuzumab), EC50=0.003729ug/mL)
CD79b recombinant antibody
Anti-CD79b Reference Antibody (polatuzumab)
Gene Names
CD79B; B29; IGB; AGM6
Reactivity
Human, Mouse, Cynomolgus
Applications
Flow Cytometry, Functional Assay, ELISA
Purity
This antibody is purified through a protein A column.
Synonyms
CD79b, Recombinant Antibody; Anti-CD79b Reference Antibody (polatuzumab); CD79b recombinant antibody
Host
CHO Cell
Reactivity
Human, Mouse, Cynomolgus
Clonality
Monoclonal
Isotype
IgG1
Specificity
CD79b
Purity/Purification
This antibody is purified through a protein A column.
Form/Format
Purified monoclonal antibody supplied in PBS, pH6.0, without preservative
Applicable Applications for CD79b recombinant antibody
FCM/FACS (Flow Cytometry), ELISA
Endotoxin
< 0.001EU/ug, determined by LAL method.
Function
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Cellular Location
Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
Tissue Location
B-cells
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at -80 degree C for 2 years under sterile conditions; -20 degree C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.
Application Data
(Immobilized human CD79b His at16 ug/mL can bind Anti-CD79b Reference Antibody (polatuzumab), EC50=0.003729ug/mL)
Application Data
(Immobilized human CD79b His at16 ug/mL can bind Anti-CD79b Reference Antibody (polatuzumab), EC50=0.003729ug/mL)
Application Data
(The purity of Anti-CD79b Reference Antibody (polatuzumab)is more than 98.12% ,determined by SEC-HPLC.)
Application Data
(The purity of Anti-CD79b Reference Antibody (polatuzumab)is more than 98.12% ,determined by SEC-HPLC.)
SDS-PAGE
(Anti-CD79b Reference Antibody (polatuzumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%)
SDS-PAGE
(Anti-CD79b Reference Antibody (polatuzumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%)
Product Categories/Family for CD79b recombinant antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
145.26 kDa
NCBI Official Full Name
B-cell antigen receptor complex-associated protein beta chain
NCBI Official Synonym Full Names
CD79b molecule, immunoglobulin-associated beta
NCBI Official Symbol
CD79B
NCBI Official Synonym Symbols
B29; IGB; AGM6
NCBI Protein Information
B-cell antigen receptor complex-associated protein beta chain; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein; CD79b antigen (immunoglobulin-associated beta)
UniProt Protein Name
B-cell antigen receptor complex-associated protein beta chain
UniProt Gene Name
CD79B
UniProt Synonym Gene Names
B29; IGB
UniProt Entry Name
CD79B_HUMAN
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Product Notes
The CD79b cd79b (Catalog #AAA296805) is a Recombinant Antibody produced from CHO Cell and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD79b Reference Antibody (polatuzumab) reacts with Human, Mouse, Cynomolgus and may cross-react with other species as described in the data sheet. AAA Biotech's CD79b can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA. Researchers should empirically determine the suitability of the CD79b cd79b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD79b, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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