IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human prostate carcinoma stained with Beta-Catenin Recombinant Rabbit Monoclonal Antibody (CTNNB1/7044R).)
Rabbit anti-Human Catenin, beta (CTNNB1) Monoclonal Antibody | anti-CTNNB1 antibody
Catenin, beta (CTNNB1) Recombinant Rabbit Monoclonal Antibody [Clone CTNNB1/7044R]
Gene Names
CTNNB1; CTNNB; MRD19; armadillo
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
Catenin, beta (CTNNB1), Antibody; Catenin, beta (CTNNB1) Recombinant Rabbit Monoclonal Antibody [Clone CTNNB1/7044R]; Cadherin associated protein, beta 1 88kDa, Catenin beta-1, CATNB, CHBCAT, CTNNB1; anti-CTNNB1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit/IgG, kappa
Clone Number
CTNNB1/7044R
Form/Format
200ug/ml of Ab purified by Protein A Column. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA at 1.0mg/ml (varies by lot)
Applicable Applications for anti-CTNNB1 antibody
IHC (Immunohistochemistry)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant full-length human β-catenin protein
Cellular Localization
Cell surface, Cytoplasm
Positive Control
Human breast carcinoma.
Hu-chromosome Location
3p22.1
Unigene
476018
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human prostate carcinoma stained with Beta-Catenin Recombinant Rabbit Monoclonal Antibody (CTNNB1/7044R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human prostate carcinoma stained with Beta-Catenin Recombinant Rabbit Monoclonal Antibody (CTNNB1/7044R).)
Related Product Information for anti-CTNNB1 antibody
Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex. In breast ductal neoplasia, beta-catenin is usually localized in cellular membranes. However, in lobular neoplasia, a marked redistribution of beta-catenin throughout the cytoplasm results in a diffuse cytoplasmic pattern. Immuno-staining of beta-catenin and E-cadherin is helps in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Additionally, some rectal and gastric adenocarcinomas demonstrate diffuse cytoplasmic beta-catenin staining and a lack of membranous staining, mimicking the staining pattern observed with lobular breast carcinomas.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
85,497 Da
NCBI Official Full Name
catenin beta-1
NCBI Official Synonym Full Names
catenin (cadherin-associated protein), beta 1, 88kDa
NCBI Official Symbol
CTNNB1
NCBI Official Synonym Symbols
CTNNB; MRD19; armadillo
NCBI Protein Information
catenin beta-1
UniProt Protein Name
Catenin beta-1
UniProt Gene Name
CTNNB1
UniProt Synonym Gene Names
CTNNB
UniProt Entry Name
CTNB1_HUMAN
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Product Notes
The CTNNB1 ctnnb1 (Catalog #AAA215580) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Catenin, beta (CTNNB1) Recombinant Rabbit Monoclonal Antibody [Clone CTNNB1/7044R] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Catenin, beta (CTNNB1) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CTNNB1 ctnnb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Catenin, beta (CTNNB1), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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