Application Data
(Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitis virus(VSV). The EC50 for this effect is typically 0.6-4.2pg/mL.)
Interferon alpha 2/IFNA2 Recombinant Protein | IFNA2 recombinant protein
Interferon alpha 2/IFNA2 Protein, Human, Recombinant
Gene Names
IFNA2; IFNA; INFA2; IFNA2B; IFN-alphaA
Purity
>95 % as determined by SDS-PAGE.
Synonyms
Interferon alpha 2/IFNA2; N/A; Interferon alpha 2/IFNA2 Protein, Human, Recombinant; Human Interferon alpha 2/IFNA2 Protein; interferon, alpha 2; IFN-alphaA Protein, Human; IFNA Protein, Human; IFNA2B Protein, Human; IFNAB Protein, Human; INFA2 Protein, Human; Interferon alpha 2 Protein, Human; IFNA2 recombinant protein
Host
Yeast
Purity/Purification
>95 % as determined by SDS-PAGE.
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Sequence Positions
165aa
Sequence
Cys24-Glu188
Species
Human
Predicted N Terminal
Cys24
Protein Construction
|A DNA sequence encoding the human IFNA2A (P01563.1) (Cys24-Glu188) was expressed
Activity
Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitis virus(VSV). The EC50 for this effect is typically 0.6-4.2pg/mL.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping: They are shipped out with blue ice pack
Shipping: They are shipped out with blue ice pack
Application Data
(Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitis virus(VSV). The EC50 for this effect is typically 0.6-4.2pg/mL.)
Application Data
(Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitis virus(VSV). The EC50 for this effect is typically 0.6-4.2pg/mL.)
Application Data
Application Data
Related Product Information for IFNA2 recombinant protein
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-alpha genes, a total of 28 different sequence variants have been described. The three principal subtypes of IFNalpha-2 are designated alpha-2a, alpha-2b, and alpha-2c. IFNalpha-2b is being the predominant allele while IFNalpha-2a is less predominant and IFNalpha-2c only a minor allelic variant.
References
Wang, et al. (2004) Fever of recombinant human interferon-alpha is mediated by opioid domain interaction with opioid receptor inducing prostaglandin E2. J Neuroimmunol. 156(1-2): 107-12.Groopman JE, et al. (1984) Recombinant alpha-2 interferon therapy for Kaposi's sarcoma associated with the acquired immunodeficiency syndrome. Ann Intern Med. 100(5): 671-6.Krueger JM, et al. (1987) Interferon alpha-2 enhances slow-wave sleep in rabbits. Int J Immunopharmacol. 9(1): 23-30.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,550 Da
NCBI Official Full Name
interferon alpha-2
NCBI Official Synonym Full Names
interferon, alpha 2
NCBI Official Symbol
IFNA2
NCBI Official Synonym Symbols
IFNA; INFA2; IFNA2B; IFN-alphaA
NCBI Protein Information
interferon alpha-2; IFN-alpha-2; alpha-2a interferon; interferon alpha 2a; interferon alpha 2b; interferon alpha A; leIF A
UniProt Protein Name
Interferon alpha-2
UniProt Gene Name
IFNA2
UniProt Synonym Gene Names
IFNA2A; IFNA2B; IFNA2C; IFN-alpha-2; LeIF A
UniProt Entry Name
IFNA2_HUMAN
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Product Notes
The IFNA2 ifna2 (Catalog #AAA257444) is a Recombinant Protein produced from Yeast and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 165aa. The amino acid sequence is listed below: Cys24-Glu1 88. It is sometimes possible for the material contained within the vial of "Interferon alpha 2/IFNA2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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