Human Metalloproteinase Inhibitor 1, TIMP1 ELISA Kit | TIMP1 elisa kit

Human Metalloproteinase Inhibitor 1, TIMP1 Primacu ELISA Kit

Cat. Num. AAA124436

• Gene Names: TIMP1; EPA; EPO; HCI; CLGI; TIMP
• Reactivity: Human
• Synonyms: Metalloproteinase Inhibitor 1, TIMP1; N/A; Human Metalloproteinase Inhibitor 1, TIMP1 Primacu ELISA Kit; Metalloproteinase inhibitor 1; TIMP-1; CLGI; TIMP; TIMP1 elisa kit

• Reactivity: Human
• Assay Type: Sandwich
• Samples: Serum, plasma, cell culture supernates
• Detection Range: 4.68-300pg/mL
• Sensitivity: 1.99pg/mL
• Standard Solution: 3ng/mL
• Assay Time: 3.5h

• Preparation and Storage: Store at 2-8 degree C

Standard Curve (Sample)

(Typical Testing Data/Standard Curve (for reference only))

Related Product Information for TIMP1 elisa kit

TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this protein encoding gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This encoding gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 is Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.

Product Categories/Family for TIMP1 elisa kit

Primacu ELISA Kit; Cancer; Cardiovascular; Cell biology; Signal transduction

NCBI and Uniprot Product Information

• NCBI GI #: 4507509
• NCBI GeneID: 7076
• NCBI Accession #: NP_003245.1
• NCBI GenBank Nucleotide #: NM_003254.2
• UniProt Accession #: P01033; Q14252; Q9UCU1
• Molecular Weight: 23,171 Da
• NCBI Official Full Name: metalloproteinase inhibitor 1
• NCBI Official Synonym Full Names: TIMP metallopeptidase inhibitor 1
• NCBI Official Symbol: TIMP1
• NCBI Official Synonym Symbols: EPA; EPO; HCI; CLGI; TIMP
• NCBI Protein Information: metalloproteinase inhibitor 1; TIMP-1; collagenase inhibitor; erythroid potentiating activity; erythroid-potentiating activity; fibroblast collagenase inhibitor; tissue inhibitor of metalloproteinases 1
• UniProt Protein Name: Metalloproteinase inhibitor 1
• UniProt Gene Name: TIMP1
• UniProt Synonym Gene Names: CLGI; TIMP; EPA; Collagenase inhibitor; TIMP-1
• UniProt Entry Name: TIMP1_HUMAN